Product Description & Research Overview

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It is one of the most extensively researched regenerative peptides due to its broad effects on tissue repair, skin rejuvenation, hair growth, and cellular health.

Natural GHK-Cu levels decline significantly with age—from approximately 200 ng/mL at age 20 to around 80 ng/mL by age 60—a reduction associated with slower wound healing, decreased collagen production, reduced skin elasticity, and other visible signs of aging.

Unlike many compounds that target a single biological pathway, GHK-Cu influences a remarkably broad range of cellular processes. Research suggests it may affect the expression of approximately 31% of human genes, promoting pathways involved in tissue regeneration while suppressing genes associated with excessive inflammation and tissue damage. This unique ability has made GHK-Cu one of the most widely studied peptides in regenerative medicine, cosmetic science, and healthy aging research.

Laboratory and animal studies have investigated GHK-Cu for its potential to stimulate collagen and elastin synthesis, promote angiogenesis (new blood vessel formation), accelerate wound healing, support hair follicle regeneration, modulate immune function, improve skin quality, and reduce oxidative stress.

Interesting Facts

• Naturally occurring GHK-Cu levels decline by approximately 60% between ages 20 and 60.
• One of the few naturally occurring peptides shown to influence approximately 31% of human gene expression in laboratory research.
• Frequently studied in regenerative medicine, dermatology, cosmetic science, and wound healing.
• Demonstrates both regenerative and anti-inflammatory properties across multiple tissue types.
• Often researched alongside BPC-157, TB-500, and CJC-1295 for tissue repair applications.

Safety & Interactions

• Generally well tolerated within researched dosing ranges.
• Avoid combining with high-dose copper supplements unless specifically being studied, as excessive copper exposure may increase toxicity risk.
• Frequently researched alongside BPC-157, TB-500, and CJC-1295 for regenerative applications.
• Use caution when combining with Melanotan II, as both may influence pigmentation pathways.